Nearly a century ago, biologists found that if they
separated an invertebrate animal embryo into two parts
at an early stage of its life, it would survive and develop
as two normal embryos. This led them to believe that the
(5) cells in the early embryo are undetermined in the sense
that each cell has the potential to develop in a variety of
different ways. Later biologists found that the situation
was not so simple. It matters in which plane [ring1] the embryo
is cut. If it is cut in a plane different from the one used
(10) by the early investigators, it will not form two whole
embryos.
A debate arose over what exactly was happening.
Which embryo cells are determined, just when do they-
become irreversibly committed to their fates, and what
(15) are the “morphogenetic determinants” that tell a cell
what to become? But the debate could not be resolved
because no one was able to ask the crucial questions
in a form in which they could be pursued productively.
Recent discoveries in molecular biology, however, have
(20) opened up prospects for a resolution of the debate.
Now investigators think they know at least some of the
molecules that act as morphogenetic determinants in
early development. They have been able o show that,
in a sense, cell determination begins even before an egg
(25) is fertilized .
Studying sea urchins, biologist Paul Gross found
that an unfertilized egg contains substances that func-
tion as morphogenetic determinants. They are located
in the cytoplasm of the egg cell; i.e., in that part of the
(30) cell’s protoplasm that lies outside of the nucleus. In the
unfertilized egg, the substances are inactive and are not
distributed homogeneously. When the egg is fertilized,
the substances become active and, presumably, govern
the behavior of the genes they interact with. Since the
(35) substances are unevenly distributed in the egg, when the
fertilized egg divides, the resulting cells are different
from the start and so can be qualitatively different in
their own gene activity.
The substances that Gross studied are maternal
(40) messenger RNA’s --products of certain of the maternal
genes. He and other biologists studying a wide variety
of organisms have found that these particular RNA’s
direct, in large part, the synthesis of histones, a class
of proteins that bind to DNA. Once synthesized, the
(45) histones move into the cell nucleus, where section of
DNA wrap around them to form a structure that resem-
bles beads , or knots, on a string. The beads are DNA
segments wrapped around the histones; the string is the
intervening DNA. And it is the structure of these beaded
(50) DNA strings that guides the fate of the cells in which
they are located.
27. According to the passage, when biologists believed that the cells in the early embryo were undetermined, they made which of the following mistakes?
(A) They did not attempt to replicate [ring10] the original experiment of separating an embryo into two parts.
(B) They did not realize that there was a connection between the issue of cell determination and the outcome of the separation experiment.
(C) They assumed that the results of experiments on embryos did not depend on the particular animal species used for such experiments.
(D) They assumed that it was crucial to perform the separation experiment at an early stage in the embryo’s life.
(E) They assumed that different ways of separating an embryo into two parts would be equivalent as far as the fate of the two parts was concerned.
以前有人讨论过此题B与E的选择,我这里是想问C错在哪里。见文中highlight部分,我觉得这里重点是在说之后生物学家发现切割不同植物的胚胎,情况会不同。可E强调是不同的切割方法, 而不是切割不同类的植物。confusing!!
请望指点!
顺便问下A:They did not attempt to replicate the original experiment.
觉得也对啊,他们没有重复实验,所以没有发现问题。Later biologists之所以发现问题,是因为重复了实验,但没得到相同结果。
It matters in which plane the embryo is cut. If it is cut in a plane different from the one used by the early investigators, it will not form two whole embryos.
27. According to the passage, when biologists believed that the cells in the early embryo were undetermined, they made which of the following mistakes?
(E) They assumed that different ways of separating an embryo into two parts would be equivalent as far as the fate of the two parts was concerned.
以前有人讨论过此题B与E的选择,我这里是想问C错在哪里。见文中highlight部分,我觉得这里重点是在说之后生物学家发现切割不同植物的胚胎,情况会不同。可E强调是不同的切割方法, 而不是切割不同类的植物。
It matters in which plane the embryo is cut. 这句话的意思是:事关胚胎是从哪个平面被切开的。xiongluanyu 可能将 plane 看成了 plant(植物)了,所以才产生了错误的理解。
顺便问下A:They did not attempt to replicate the original experiment.
觉得也对啊,他们没有重复实验,所以没有发现问题。Later biologists之所以发现问题,是因为重复了实验,但没得到相同结果。
According to the passage, when biologists believed that the cells in the early embryo were undetermined, they made which of the following mistakes?
题干问:当生物学家(过去)相信早期胚胎的细胞(对基因)不具确定性时,他们犯了一个什么样的错误。
(E) They assumed that different ways of separating an embryo into two parts would be equivalent as far as the fate of the two parts was concerned.
(E)选项的意思是:他们假定用不同的方法把胚胎切成两半对于如何决定两部分的命运是一样的(不相关的)。——正确选项。
(A)选项说:他们没有尝试去重复最初的实验。说的是他们为什么没有发现正确的理论,而不是说生物学家犯了一个什么样的错误。
另外,借楼主的文章问一道题。
It can be inferred from the passage that the morphogenetic determinants present in the early embryo are
(A) located in the nucleus of the embryo cells
(B) evenly distributed unless the embryo is not developing normally
(C) inactive until the embryo cells become irreversibly committed to their final function
(D) identical to those that were already present in the unfertilized egg
(E) present in larger quantities than is necessary for the development of a single individual
我觉得上题的正确答案应该是(C)选项,而蓝皮书(第159页)的标准答案是(E)。请问大家讨论一下。
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